AZILECT (rasagiline tablets) is indicated for the treatment of the signs and symptoms
of Parkinson’s disease (PD) both as initial therapy alone and to be added to levodopa
later in the disease.
IMPORTANT SAFETY INFORMATION ABOUT AZILECT
Do not take Azilect if you are taking meperidine as it could result in a serious
reaction such as coma or death. Also, do not take Azilect with tramadol, methadone,
propoxyphene, dextromethophran, St. John’s wort, or cyclobenzaprine. You also should
not take Azilect with other monoamine oxidase inhibitors (MAOIs).
Inform your physician if you are taking, or planning to take, any prescription or
over-the-counter drugs, especially antidepressants and ciprofloxacin. If you have
moderate to severe liver disease, you should not take Azilect. You should not exceed
a dose of 1 mg per day of Azilect in order to prevent a possibly dangerous increase
in blood pressure. All PD patients should be monitored for melanoma (skin cancer)
on a regular basis.
Side effects seen with Azilect alone are flu syndrome, joint pain, depression, and
indigestion: and when taken with levodopa are uncontrolled movements (dyskinesia),
accidental injury, weight loss, low blood pressure when standing, vomiting, anorexia,
joint pain, abdominal pain, nausea, constipation, dry mouth, rash, abnormal dreams,
and fall.
You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit www.fda.gov/medwatch,
or call 1-800-FDA-1088.
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